Pfizer's EMBLAVEO® for Sufferers with Multidrug-resistant Infections and Restricted Remedy Choices – The Journal of Healthcare Contracting

Pfizer's EMBLAVEO® for Sufferers with Multidrug-resistant Infections and Restricted Remedy Choices – The Journal of Healthcare Contracting



April 25, 2024 – Pfizer Inc. has introduced that the European Fee (EC) has granted a advertising authorization for EMBLAVEO® (aztreonam-avibactam) for the remedy of grownup sufferers with difficult intra-abdominal infections (cIAI), community-acquired pneumonia (HAP), together with ventilator-associated pneumonia (VAP), and complex urinary tract infections (cUTI), together with pyelonephritis. It is usually indicated for the remedy of infections brought on by cardio gram-negative organisms in grownup sufferers with restricted remedy choices.

Antimicrobial resistance (AMR) – when micro organism, viruses, fungi and parasites change and discover methods to withstand the consequences of antimicrobial medication – is acknowledged as one of many biggest threats to world well being. If AMR continues to rise unchecked, minor infections can turn out to be life-threatening and plenty of routine medical procedures similar to cesarean sections and hip replacements can turn out to be too dangerous to carry out. Multidrug-resistant Gram-negative micro organism are of explicit concern due to the excessive morbidity and mortality they trigger. Metallo-β-lactamases (MBLs) are a kind of enzyme produced by sure micro organism that may result in antibiotic resistance, and MBL-producing gram-negative micro organism are on the rise worldwide.

It’s deliberate that functions for a advertising authorization for EMBLAVEO can be submitted in different nations.

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