June 27, 2024 – Thermo Fisher Scientific Inc. introduces the Thermo Scientific™ KingFisher™ PlasmidPro Maxi Processor (PlasmidPro), the business’s solely totally automated maxi-scale plasmid DNA (pDNA) purification system. PlasmidPro allows innovation at scale, providing full automation for mini- and maxi-scale purification, and delivering high-purity plasmid with out guide column preparation and intervention. That is the newest addition to the Thermo Scientific KingFisher instrument portfolio, which presents a variety of plasmid DNA extraction merchandise to drive effectivity and consistency.
There are roughly 1,700 medical trials of cell and gene therapies worldwide.1 Lately, plasmids have been instrumental within the improvement of cell and gene therapies, monoclonal antibody and mRNA therapies, and vaccines. Plasmids are generally utilized in varied molecular biology purposes, together with transfection, protein expression, gene remedy, DNA sequencing, and vaccine improvement. They’re a vital laboratory instrument that may function a service to ship desired genes or DNA fragments into goal cells.
The PlasmidPro Purification System requires no setup, centrifugation or pipetting and totally automates the purification course of from tradition to plasmid. The product makes use of a self-contained cartridge pre-filled with all obligatory reagents to carry out the purification, eliminating the necessity for added devices and plastics and minimizing setup time and contamination dangers. Utilizing 100-150 ml of recent in a single day tradition, the system can produce a DNA yield of as much as 1.5 mg.
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